Trim the brisket if desired. Salt the meat on both sides and leave it at room temperature for about 45 minutes. Meanwhile, prepare your smoker, setting it to 225 degrees
Mix all seasonings besides the salt together in a small bowl. Then, use your fingertips to spread the rub on both sides of the brisket, gently pressing it into the meat
Transfer the brisket to the smoker, ensuring that the thicker part is closer to the heat source for more reliable, thorough cooking. Cook for several hours until the meat temperature reaches about 165 degrees
Wrap the brisket, if desired, using the instructions above. Return the meat to the smoker to continue cooking until it reaches about 200 degrees. The total time is typically between 10-12 hours
Remove the brisket from the smoker and let it rest at room temperature for up to 30 minutes
Slice the brisket against the grain or shred it using two forks for serving. Enjoy!