Fill the smoker’s wood pan with hickory or oak wood, and set the temperature to 225°F.
In a bowl, gently mix the ground brisket with salt, pepper, garlic powder, and Worcestershire sauce. Form into four patties, about ¾-inch thick.
Place the patties in the smoker and cook for 1 hour or until they reach an internal temperature of 135-140°F for medium doneness.
For a crispier exterior, sear the patties on a hot grill or skillet for 1-2 minutes per side.
Place patties on toasted buns and add your favorite toppings and condiments.